WORKS
主な業績、活動実績は下記のとおりです。
研究業績の詳細については”research map”もご参照ください。
Nakakubo S, Doi T, Tsutsumimoto K, Kiuchi Y, Nishimoto K, Shimada H. Long sleep duration and sarcopenia according to physical activity level in community-dwelling older adults. Geriatr Gerontol Int, 2026.[Epub ahead of print]
Nakakubo S, Doi T, Tsutsumimoto K, Kiuchi Y, Nosaka S, Abe K, Shimada H. Association of Long Sleep and Physical Inactivity With Incident Disability in Community-Dwelling Older Adults: A 5-year Longitudinal Study. J Appl Gerontol, 2026. 7334648261452329.
Ohura T, Doi T, Oka T, Sakimoto F, Matsuda S, Nishimura M, Shimada H. Understanding improvements in self-efficacy and engagement with the Long-term care Information system For Evidence (LIFE) workshop in Japan. JBI Evid Implement, 2026. [Epub ahead of print]
Matsuda S, Doi T, Harada K, Nakakubo S, Sakimoto F, Nosaka S, Abe K, Shimada H. Dorsolateral prefrontal cortex hemispheric asymmetry and chronic low back pain at 8-year follow-up in community-dwelling older adults. Geroscience, 2026. [Epub ahead of print]
Vazquez J, Allali G, Beauchet O, Callisaya ML, Doi T, Kumar P, Milman S, Shimada H, Srikanth V, Verghese J, Blumen H. Cerebral small vessel disease unveils a vascular pathway to motoric cognitive risk in aging. J Alzheimers Dis, 109(3):1211-1219, 2026.
Shimada H, Lee S, Doi T, Takayanagi N, Sudo M, Yamashiro Y, Niki Y, Arai H. Community walking speed as a new predictor of disability incidence in older adults: A prospective cohort study. Gerontology: 1-18, 2026. [Epub ahead of print]
Sakimoto F, Doi T, Nakakubo S, Matsuda S, Makino K, Shimada H. Impact of Lifestyle Activity Engagement on Incident Disability: A Stratified Analysis by Cardiovascular Disease Risk. Neuroepidemiology: 1-9, 2025. [Epub ahead of print]
Kurita S, Doi T, Harada K, Morikawa M, Nishijima C, Fujii K, Kakita D, Shimada H. Health-related and socio-demographic factors for self-monitoring of daily activities among community-dwelling older adults. J Public Health (Oxf), 47(4): 747-755, 2025.
Sakimoto F, Doi T, Nakakubo S, Matsuda S, Shimada H. Engagement in cognitive activities and risk of loneliness: A longitudinal study among Japanese older adults. Arch Gerontol Geriatr, 141: 106061, 2025. [Epub ahead of print
Blumen HM, Delpratt N, Beauchet O, Callisaya ML, Doi T, Kumar VP, Lipton RB, Milman S, Shimada H, Srikanth V, Verghese J. Sex-specific brain atrophy patterns associated with the motoric cognitive risk syndrome. J Alzheimers Dis, 108(2): 597-605, 2025.
Matsuda S, Doi T, Harada K, Nakakubo S, Katayama O, Sakimoto F, Shimada H. Brain structural asymmetry associated with cognitive impairment in community-dwelling older adults. Arch Gerontol Geriatr, 138: 105975, 2025.
Sakimoto F, Doi T, Katayama O, Matsuda S, Makino K, Shimada H. Exploring lifestyle activities as possible protective factors for life satisfaction: a cross-sectional study. BMC Geriatr, 25(1): 812, 2025.
Doi T, Nakakubo S, Sakimoto F, Matsuda S, Shimada H. Association between the frequency of going outdoors by life space and incident disability among older adults. J Frailty Aging, 14(5): 100070, 2025.
Nallapu BT, Ezzati A, Blumen HM, Petersen KK, Lipton RB, Ayers E, Kumar VGP, Velandai S, Beare R, Beauchet O, Doi T, Shimada H, Callisaya M, Milman S, Aleksic S, Verghese J. Discovering subtypes with imaging signatures in the Motoric Cognitive Risk Syndrome Consortium using weakly supervised clustering. Alzheimers Dement (Amst), 17(4): e70197, 2025.
Sakimoto F, Doi T, Ishii H, Matsuda S, Makino K, Shimada H. Lifestyle activities to protect against depressive symptoms after driving cessation among older adults: A longitudinal study. Geriatr Gerontol Int, 25(10): 1316-1322, 2025.
Matsuda S, Doi T, Nakakubo S, Sakimoto F, Shimada H. The Combined Effects of Chronic Pain and Different Types of Isolation on the Incidence of Disability in Community-Dwelling Older Adults: Prospective Cohort Study. J Am Med Dir Assoc, 26(9): 105748, 2025.
Sakimoto F, Doi T, Tomida K, Matsuda S, Makino K, Shimada H. Cognitive activity levels associated with dementia risk in older adults with social frailty: A longitudinal study. Maturitas, 198: 108597, 2025.
Matsuda S, Doi T, Nakakubo S, Sakimoto F, Shimada H. Protective Effects of Social Activity on the Disability Incidence among Community-Dwelling Older Adults with Chronic Pain. J Am Med Dir Assoc, 26(6): 105623, 2025.
Tanaka S, Ihira H, Tajima T, Kanehara R, Inoue Y, Doi T, Kobayashi N, Kato Y, Nishita Y, Konishi M, Nakao YM, Kabe I, Morioka C, Dohi S, Khairan P, Arafa A, Narita ZC, Morisaki N, Lu Y, Otsuka R, Yamaji T, Shimada H, Mizoue T, Sawada N, Tsugane S, Iwasaki M, Inoue M. Birth cohort-specific smoking patterns in Japan (1906–2004): a population-based study from the NC-CCAPH consortium. Lancet Reg Health-W, 58: 101562, 2025.
Shimada H, Doi T, Tsutsumimoto K, Makino K, Harada K, Tomida K, Morikawa M, Arai H. Combined effects of social isolation and loneliness on disability incidence in older adults. Arch Gerontol Geriatr, 131: 105749, 2025.
Matsuda S, Doi T, Katayama O, Makino K, Sakimoto F, Shimada H. Association of chronic low back pain and knee pain with subjective fatigue incidence among community-dwelling older adults: A prospective cohort study. Geriatr Gerontol Int, 25(3): 398-402, 2025.
Shimada H, Doi T, Tsutsumimoto K, Makino K, Harada K, Tomida K, Morikawa M, Makizako H. A New Computer-Based Cognitive Measure for Early Detection of Dementia Risk (Japan Cognitive Function Test): Validation Study. J Med Internet Res, 27: e59015, 2025.
Doi T, Makino K, Tomida K, Tsutsumimoto K, Sakimoto F, Matsuda S, Shimada H. Life-Space Activities and Incident Dementia Among Older Adults: Insights From a Cohort Study. J Am Med Dir Assoc, 26(2): 105416, 2025.
Inoue Y, Suzuki S, Sawada N, Morisaki N, Narita Z, Yamaji T, Kokubo Y, Doi T, Nishita Y, Iwasaki M, Inoue M, Mizoue T. Association between physical multimorbidity in middle adulthood and mortality: findings from two large cohort studies in Japan. BMC Public Health, 25(1): 92, 2025.
Matsuda S, Doi T, Katayama O, Sakimoto F, Makino K, Sudo M, Yamashiro Y, Takayanagi N, Shimada H. Chronic low back pain and decreased physical activity are associated with social frailty incidence among community-dwelling older adults. Geriatr Gerontol Int, 25(1): 25-30, 2025.
Shimada H, Ishii H, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Arai H. Study protocol of the safe driving program for the prevention of car accidents: A randomized controlled trial protocol. Geriatr Gerontol Int, 24(11): 1218-1222, 2024.
Sawa R, Doi T, Tsutsumimoto K, Nakakubo S, Sakimoto F, Matsuda S, Shimada H. Association Between Falls and Social Frailty in Community-Dwelling Older Japanese Adults. J Gerontol B Psychol Sci Soc Sci, 79(9): gbae127, 2024.
Kurita S, Doi T, Harada K, Morikawa M, Nishijima C, Fujii K, Kakita D, Shimada H. Subjective memory concerns and car collisions: A cross-sectional cohort study among older Japanese drivers. Heliyon, 10(12): e33080, 2024.
Shimoda T, Tomida K, Nakajima C, Kawakami A, Doi T, Shimada H. Impact of working time and industry type on disability incidence among older Japanese adults. Discover Public Health, 21(1): 10, 2024.
Sakurai T, Sugimoto T, Akatsu H, Doi T, Fujiwara Y, Hirakawa A, Kinoshita F, Kuzuya M, Lee S, Matsumoto N, Matsuo K, Michikawa M, Nakamura A, Ogawa S, Otsuka R, Sato K, Shimada H, Suzuki H, Suzuki H, Takechi H, Takeda S, Uchida K, Umegaki H, Wakayama S, Arai H, J-MINT study group. Japan-Multimodal Intervention Trial for the Prevention of Dementia: A randomized controlled trial. Alzheimers Dement, 20(6): 3918-3930, 2024.
Makino K, Doi T, Tsutsumimoto K, Katayama O, Yamaguchi R, Georg VF, Yamagiwa D, Makizako H, Shimada H. Impacts of Negative and Positive Life Events on Development of Social Frailty among Community-Dwelling Older Adults. J Am Med Dir Assoc, 25(4): 690-696 e1, 2024.
Shimada H, Doi T, Tsutsumimoto K, Makino K, Harada K, Tomida K, Morikawa M, Arai H. Combined impact of physical frailty and social isolation on use of long-term care insurance in Japan: A longitudinal observational study. Maturitas, 182: 107921, 2024.
Doi T, Tsutsumimoto K, Makino K, Nakakubo S, Sakimoto F, Matsuda S, Shimada H. Combined Social Frailty and Life-Space Activities Associated with Risk of Disability: A Prospective Cohort Study. J Frailty Aging, 13(2): 184-188, 2024.
Shimada H, Doi T, Tsutsumimoto K, Makino K, Harada K, Tomida K, Arai H. Elevated Risk of Dementia Diagnosis in Older Adults with Low Frequencies and Durations of Social Conversation. J Alzheimers Dis, 98(2): 659-669, 2024.
Kiuchi Y, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Nishimoto K, Makizako H, Shimada H. Association between dietary diversity and cognitive impairment in community-dwelling older adults. Geriatr Gerontol Int, 24(1): 75-81, 2024.
Ishii H, Okubo Y, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Uemura K, Misu S, Sawa R, Hashiguchi Y, Shimada H, Arai H. Effect of driving training on car crashes and driving skills in older people: A systematic review and meta-analysis. Geriatr Gerontol Int, 23(11): 771-778, 2023.
Kiuchi Y, Tsutsumimoto K, Doi T, Kurita S, Nishimoto K, Makizako H, Shimada H. Effect of dietary diversity on incident of disability in community-dwelling older adults with sarcopenia: A 40-month follow-up longitudinal study. Maturitas, 179: 107887, 2024.
Nishimoto K, Tsutsumimoto K, Doi T, Kurita S, Kiuchi Y, Shimada H. Urinary incontinence and life-space activity/mobility additively increase the risk of incident disability among older adults. Maturitas, 179: 107870, 2024.
Shimada H, Doi T, Tsutsumimoto K, Makino K, Harada K, Tomida K, Arai H. Predictive Validity of Different Walking Measures to Identify the Incident Long-Term Care Needs in Older Adults. J Nutr Health Aging, 27(9): 759-766, 2023.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Kiuchi Y, Nishimoto K, Shimada H. Self-Monitoring of Physical, Cognitive, and Social Activities and 2-Year Disability Onset in Community-Dwelling Older Adults. J Am Med Dir Assoc, 24(10): 1497-1502, 2023.
Sawa R, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Kiuchi Y, Nishimoto K, Shimada H. Overlapping status of frailty and fear of falling: an elevated risk of incident disability in community-dwelling older adults. Aging Clin Exp Res, 35(9): 1937-1944, 2023.
Kurita S, Doi T, Harada K, Katayama O, Morikawa M, Nishijima C, Fujii K, Misu Y, Yamaguchi R, Von Fingerhut G, Kakita D, Shimada H. Motoric Cognitive Risk Syndrome and Traffic Incidents in Older Drivers in Japan. JAMA Netw Open, 6(8): e2330475, 2023.
Shimada H, Suzuki T, Doi T Lee S, Nakakubo S, Makino K, Arai H. Impact of osteosarcopenia on disability and mortality among Japanese older adults. J Cachexia Sarcopenia Muscle, 14(2): 1107-1116, 2023.
Abe SK, Ihira H, Minami T, Imatoh T, Inoue Y, Tsutsumimoto K, Kobayashi N, Kashima R, Konishi M, Doi T, Teramoto M, Kabe I, Lee S, Watanabe M, Dohi S, Sakai Y, Nishita Y, Morisaki N, Tachimori H, Kokubo Y, Yamaji T, Shimada H, Mizoue T, Sawada N, Tsugane S, Iwasaki M, Inoue M. Prevalence of family history of cancer in the NC-CCAPH consortium of Japan. Sci Rep, 13(1): 3128, 2023.
Kiuchi Y, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Nishimoto K, Makizako H, Shimada H. Association between dietary diversity and sarcopenia in community-dwelling older adults. Nutrition, 106: 111896, 2023.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Kiuchi Y, Nishimoto K, Shimada H. Associations between Active Mobility Index and objectively measured physical activity among older adults. Aging Clin Exp Res, 35(1): 147-153, 2023.
Groeger JL, Ayers E, Barzilai N, Beauchet O, Callisaya M, Torossian MR, Derby C, Doi T, Lipton RB, Milman S, Nakakubo S, Shimada H, Srikanth V, Wang C, Verghese J. Inflammatory biomarkers and motoric cognitive risk syndrome: Multicohort survey. Cereb Circ Cogn Behav, 3: 100151, 2022.
Doi T, Nakakubo S, Tsutsumimoto K, Kurita S, Kiuchi Y, Nishimoto K, Shimada H. The association of white matter hyperintensities with motoric cognitive risk syndrome. Cereb Circ Cogn Behav, 3: 100150, 2022.
Nishimoto K, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Kiuchi Y, Shimada H. Relationship between Diabetes Status and Sarcopenia in Community-Dwelling Older Adults. J Am Med Dir Assoc, 23(10): 1718.e7-1718.e12, 2022.
Kato G, Doi T, Arai H, Shimada H. Cost-effectiveness Analysis of Combined Physical and Cognitive Exercises Programs Designed for Preventing Dementia among Community-dwelling Healthy Young-old Adults. Phys Ther Res, 25(2): 56-67, 2022.
Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Ishii H, Shimada H. Associations Between Active Mobility Index and Disability. J Am Med Dir Assoc, 23(8): 1335-1341, 2022.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Kiuchi Y, Nishimoto K, Shimada H. Association between Active Mobility Index and sarcopenia among Japanese community-dwelling older adults. J Cachexia Sarcopenia Muscle, 13(3): 1919-1926, 2022.
Shimada H, Doi T, Lee S, Tsutsumimoto K, Bae S, Makino K, Nakakubo S, Arai H. Identification of Disability Risk in Addition to Slow Walking Speed in Older Adults. Gerontology, 68(6): 625-634, 2022.
Nakakubo S, Doi T, Tsutsumimoto K, Kurita S, Ishii H, Suzuki T, Shimada H. The Association of Sleep Habits and Advancing Age in Japanese Older Adults: Results from the National Center for Geriatrics and Gerontology Study of Geriatric Syndromes. Gerontology, 68(2): 209-213, 2022.
Doi T, Tsutsumimoto K, Ishii H, Nakakubo S, Kurita S, Kiuchi Y, Nishimoto K, Shimada H. Impact of social frailty on the association between driving status and disability in older adults. Arch Gerontol Geriatr, 99: 104597, 2022.
Makizako H, Shimada H, Tsutsumimoto K, Makino K, Nakakubo S, Ishii H, Suzuki T, Doi T. Physical Frailty and Future Costs of Long-Term Care in Older Adults: Results from the NCGG-SGS. Gerontology, 67(6): 695-704, 2021.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Ishii H, Kiuchi Y, Shimada H. Predictivity of International Physical Activity Questionnaire Short Form for 5-Year Incident Disability Among Japanese Older Adults. J Phys Act Health, 18(10): 1231-1235, 2021.
Ishii H, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Shimada H. Driving cessation and physical frailty in community-dwelling older adults: A longitudinal study. Geriatr Gerontol Int, 21(11): 1047-1052, 2021.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Ishii H, Shimada H. Computer use and cognitive decline among Japanese older adults: A prospective cohort study. Arch Gerontol Geriatr, 97: 104488, 2021.
Kiuchi Y, Makizako H, Nakai Y, Taniguchi Y, Tomioka K, Sato N, Wada A, Doi T, Kiyama R, Takenaka T. Associations of alpha-actinin-3 genotype with thigh muscle volume and physical performance in older adults with sarcopenia or pre-sarcopenia. Exp Gerontol, 154: 111525, 2021.
Sugimoto T, Sakurai T, Akatsu H, Doi T, Fujiwara Y, Hirakawa A, Kinoshita F, Kuzuya M, Lee S, Matsuo K, Michikawa M, Ogawa S, Otsuka R, Sato K, Shimada H, Suzuki H, Suzuki H, Takechi H, Takeda S, Umegaki H, Wakayama S, Arai H. The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial. J Prev Alzheimers Dis, 8(4): 465-476, 2021.
Doi T, Nakakubo S, Tsutsumimoto K, Kurita S, Ishii H, Shimada H. Spatiotemporal gait characteristics and risk of mortality in community-dwelling older adults. Maturitas, 151: 31-35, 2021.
Nakakubo S, Doi T, Tsutsumimoto K, Kurita S, Ishii H, Shimada H. Sleep duration and progression to sarcopenia in Japanese community-dwelling older adults: a 4 year longitudinal study. J Cachexia Sarcopenia Muscle, 12(4): 1034-1041, 2021.
Blumen HM, Schwartz E, Allali G, Beauchet O, Callisaya M, Doi T, Shimada H, Srikanth V, Verghese J. Cortical Thickness, Volume, and Surface Area in the Motoric Cognitive Risk Syndrome. J Alzheimers Dis, 81(2): 651-665, 2021.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Ishii H, Shimada H. Development of a Questionnaire to Evaluate Older Adults’ Total Sedentary Time and Sedentary Time With Cognitive Activity. J Geriatr Psychiatry Neurol: 8919887211006468, 2021.
Doi T, Tsutsumimoto K, Ishii H, Nakakubo S, Kurita S, Shimada H. Frailty and driving status associated with disability: a 24-month follow-up longitudinal study. BMJ Open, 11(4): e042468, 2021.
Doi T, Tsutsumimoto K, Ishii H, Nakakubo S, Kurita S, Shimada H. Association between Sarcopenia, Its Defining Indices, and Driving Cessation in Older Adults. J Nutr Health Aging, 25(4): 462-466, 2021.
Shimada H, Tsutsumimoto K, Doi T, Lee S, Bae S, Nakakubo S, Makino K, Arai H. Effect of Sarcopenia Status on Disability Incidence Among Japanese Older Adults. J Am Med Dir Assoc, 22(4): 846-852, 2021.
Ishii H, Doi T, Tsutsumimoto K, Nakakubo S, Kurita S, Shimada H. Long-Term Effects of Driving Skill Training on Safe Driving in Older Adults with Mild Cognitive Impairment. J Am Geriatr Soc, 69(2): 506-511, 2021.
Doi T, Ishii H, Tsutsumimoto K, Nakakubo S, Kurita S, Shimada H. Car Accidents Associated with Physical Frailty and Cognitive Impairment. Gerontology, 66(6): 624-630, 2020.
Tsutsumimoto K, Doi T, Nakakubo S, Kim M, Kurita S, Ishii H, Shimada H. Association between anorexia of ageing and sarcopenia among Japanese older adults. J Cachexia Sarcopenia Muscle, 11(5): 1250-1257, 2020.
Shimada H, Doi T, Tsutsumimoto K, Lee S, Bae S, Arai H. Behavioral Factors Related to the Incidence of Frailty in Older Adults. J Clin Med, 9(10): 3074, 2020.
Kurita S, Doi T, Tsutsumimoto K, Nakakubo S, Kim M, Ishii H, Shimada H. Association of Physical Activity and Cognitive Activity With Disability: A 2-Year Prospective Cohort Study. Phys Ther, 100(8): 1289-1295, 2020.
Ishii H, Tsutsumimoto K, Doi T, Nakakubo S, Kim M, Kurita S, Shimada H. Effects of comorbid physical frailty and low muscle mass on incident disability in community-dwelling older adults: A 24-month follow-up longitudinal study. Maturitas, 139: 57-63, 2020.
Sawa R, Asai T, Doi T, Misu S, Murata S, Ono R. The Association Between Physical Activity, Including Physical Activity Intensity, and Fear of Falling Differs by Fear Severity in Older Adults Living in the Community. J Gerontol B Psychol Sci Soc Sci, 75(5): 953-960, 2020.
Tsutsumimoto K, Doi T, Nakakubo S, Kim M, Kurita S, Ishii H, Shimada H. Cognitive Frailty as a Risk Factor for Incident Disability During Late Life: A 24-Month Follow-Up Longitudinal Study. J Nutr Health Aging, 24(5): 494-499, 2020.